MHPCA was incorporated in January 1980 and received its 501(c)3 tax exempt non-profit status in January 1981. For eleven years MHPCA was supported solely by volunteer efforts. In 1991 a part-time Executive Secretary was hired to assist with the increasing organizational and communication needs. In 1992 MHPCA through the encouragement of the National Hospice and Palliative Care Organization (NHPCO) and in an effort to strengthen state organization hired a full-time Executive Director.
Through the years, MHPCA has provided educational and technical assistance to the growing number of hospice programs in the state encouraging growth and quality of service. Missouri hospices are linked in partnership with one another. Missouri hospices all have a goal of serving terminally ill patients and their families. Missouri hospices share resources, ideas, support and encouragement with one another.